Systemic juvenile idiopathic arthritis (sJIA) is the form of childhood arthritis whose treatment is most challenging.The demonstration of the prominent involvement of interleukin (IL)-1 in disease pathogenesis has provided the rationale for the treatment with biologic medications that antagonize this cytokine.The three IL-1 blockers that have been
We present the synthesis and biological evaluation of the prototype of a new class of cephalosporins, containing an additional isolated beta lactam ring with two Decals phenyl substituents.This new compound is effective against Gram positive microorganisms, with a potency similar to that of ceftriaxone, a cephalosporin widely used in clinics and ta
Recent debates in social anthropology on land acquisitions highlight the need to go further back in history in order to analyse their impacts on local livelihoods.The debate over the commons in economic and ecological anthropology helps us understand some of today’s dynamics by looking at precolonial common property institutions and the way t
Pseudoaneurysms of the common iliac artery caused by Brucellosis are exceedingly uncommon.Infected common iliac artery pseudoaneurysms, particularly those caused by brucellosis, are more difficult to diagnose and cure than general TWEEK pseudoaneurysms.The risk of mortality is significantly high in this condition.Nonsurgical treatment of a brucello
Abstract Background Coronavirus disease 2019 (COVID-19) is now a global public threat.Given the pandemic of COVID-19, the economic impact of COVID-19 is essential to add value to the policy-making process.We retrospectively conducted a cost and affordability analysis to determine the medical costs of COVID-19 patients in China, and also assess the